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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c9a5e00dc8308c6f26ed8c505ccaad28cd03fe08335d7ae9871d08c53211937' 
  AND token = '4d1PpjpTI/27rbNJLCoeYbuaaT8KlireIP2s3ObR6hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}