SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f4543f2fd94754057acecaa8e9f954294591b52e37cc201219739b74a8e5fb' 
  AND token = 'jSnQLzuPSdlH7vOjFgdPD4kUPspBj2Y05YxkOgx6Y9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}