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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f41aedd6da619b15054d6a6f9e13d9cb0fe129995a7663f6d3ed5100ef0e8e8' 
  AND token = 'D1AadGNMw/sfIKMMyHtdvEmdx3aXfqanIvDNfS3+vHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}