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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6b221db7502a5225d0a63944d685555e649fe8dfbbe67c91ab5b2051b04802' 
  AND token = 'x/CG5f32EsmX70A89hVg+NJDFrr0MNFyjy+uqQUNyrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}