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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6e91cf5b209f212142cba5077c04c14a539b5c2c85ce7f8f2d049aeca17279' 
  AND token = 'WVhakNXzziFy3NH4zK9qMcLurOsc5iesNm4EzKiRAi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}