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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dacf81beb8c24d7f179d46991336fef0cd537b0f8fc8900faa5f13845854752' 
  AND token = '3s5nxK/C0sb3AN9hd+WZafosFTtOWLmjy39L+vsOm5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}