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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed294046ce44c9edca3b4075eb2d5f4d6a1619012fa12fd40d49bc2f80753ed0' 
  AND token = 'geVHlMNI0cNzoS2kALIanWiA2BoOUxGsQxb8ilMlDy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}