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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290c4f21f7ac648b4cc84832bd05bd400c36201faee2904a201d434f6c8b6f55' 
  AND token = 'wJhICPypeimZL65K6T1J+g07zLhUzX3S+OpRoPynbnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}