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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f22e259265f001c13c9f269ec36f73e7d04084bad823045b6bfcc2a095521c' 
  AND token = 'Y7xan9sOvdgTnJgX05OlJv0HfCyx9covzkMnT5WLz0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}