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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229d291dcd0f2730304fe0a3b613aa630a5c98a95b39b688079e90a672ca8f4d' 
  AND token = 'E5L0KZrtX0XK/+agnQeQui8/KH+u3YmN4u7YrQCpRbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}