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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778141b27c3ac2f7a3ad9b2bf966cbda010ef4c19aace0b5c9d894d6cc24fd4e' 
  AND token = 'qxDxUwm7PlnOmaf9vgluqJ0JRpXx6cA/SqMumwbWnl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}