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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d43239a8f71eacdf2aeb246ff3add4b35767b40db4c66a59dd72fba7fc4181' 
  AND token = 'wHz80uMAMOARrITS95YD57cW1N6iJKeQJwn72yH+cMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}