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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8dc4c8f7332acf44a059c7d0f7e1208eb8baa75e84ab7424438c3bd07815a7' 
  AND token = 'Bcpu+0jRw9nrp4h2d2e6F0dEDZRCU4nFpWUSRStOVSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}