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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e96fb485202b5f74b7d0995f389795e8f61c53f153eb0251059bf29446d6f2bb' 
  AND token = 'VDrN4s9xMuIiGZpIT6nSBYhKc4hkFe2myrf5E4/tNVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}