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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f665331c9c6ccd2f30e57d6b51c526d225fc27431fac8c25617eaedb39a2cd8' 
  AND token = 'MGTIqUzbfzfEpVdfishjAM4MMtRbXx9+Z0rofp/I9/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}