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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51075d5258bf2553cd0aa64a2ed499802133e50577c9854a05b57afed7e0556' 
  AND token = 'KsSaYnDc525E9Rjpj2EASzca8FUVD9Fnucnvl0E1X3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}