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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5102665bf66941fcbc4ad00171d1d535e1ed07cfcfdc7168558807fa94d58d2e' 
  AND token = 'fCpdgrFF+Nz991RxBFCk5O6ndO/FoCBfzXr0Y2gzS/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}