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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730904af33f7ee24c4a46d5b722d43e6d320153ff3770a52048b7eac1a726646' 
  AND token = 'vDi41XO9DUPFvV3eUeC7/PK78xUCch+SafEjZGQmnTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}