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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca8853416efc03acf24d047274cc64788e97a2b47bb8b95e7e39faeb88bb313' 
  AND token = 'sTZhbll8HUHlsugyXXhN885mpEFU5YMV4rcaVxRZ9mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}