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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5297af70a6fb171e97771e8d175a0576c5e162e481e0bad5797238687267a2' 
  AND token = 'A4zG+VUZScXwMhMP5Fipsj+PzacHfSQbv6EFqeFB9lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}