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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450d7cb5ce3a9b02bd382ea0d711e08ee154a6bd8b17f10ca8625908df06635c' 
  AND token = 'cz16cqiFhdpuf+d/20Chy6NSsEqfRv2wsBt8Mhjduho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}