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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa7e43102ce557259a8f640bc8e0250158e0b673d9cc559f95606a7f3f2c0bc' 
  AND token = 'pVJjcjdXM/Rhh2shALPZpGLfW3AFP0T9M6cMsK25C0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}