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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3abb4a80307b5873c9243173062d9f317a49de7eb1f8413521d7bfaa0b98f3' 
  AND token = 'TgeuU3VHz4K0fZzsVmq8I4CmLmRz/klPNMYbS2gYnaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}