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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8621ba909a93eaa2bd28ed4d976e6a9e5191fd1c0f699257e5dc6fbfbd67f8b3' 
  AND token = 'ZM0KuJMvIZHWQC+JICA5Wvnr7TnXw40PXweEtfB8xtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}