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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b1417f0b22bffdbbf3d17acde3e253f01f38cd23b1bd804586c989b35f1db5' 
  AND token = 'PPLQpu7IAWpQKbMNiKxb/C58bkuUdNDyo4T/Aw4Bbec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}