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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4dffd78b6a57e24f34c88146502620a8bdc6dbe73017f7f65c2c0c875b9865' 
  AND token = 'RavrgMdASjXikfXsd3kLbhgD4op56DrJuBO8F1XlrWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}