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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f63d2c46e2c7b9badc76dfeab82659519218441bda9cfc2f8dcceaa286d4bd2' 
  AND token = 'xiVS1l8nlF3TYKvuS85BzQ4Qjie1IDgKFxNwTHPOYm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}