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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d09f0cb246c6b01a47a8161ba70cfd94931c8511821f96119f99839abc9036' 
  AND token = 'OO32dkWbvf+WvevRn3Ij2vc1UdrYTImV/UL8rVsaQJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}