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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cba17024aae13af269b573a651e9b787211e8bf3a022af5b518846077977059' 
  AND token = 'ctwBI9lTNEYnqXdUzTI5r8rFCjGDh591HcqqbzBvzEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}