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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48853dfc8d14317c8d57a0d8b882538bdede6bf5205ce4fcfb8e0289fc52e7d3' 
  AND token = 's2hzbe6v3GR4iABDt7wRxdddUIS7JU6wXNS3rSOYadM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}