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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927a68b3876b211070cb087c8a3bf9f23b2bff659169f5bf916983254ebb2251' 
  AND token = 's6ecH4skEnaILVabmgH5vZzdm2NnNsmElptl/kJMwTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}