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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c8eb9003eb7e457802e9e6ce090f8a86eb5fd0a6a68eb5e8e2cae727eab1b7' 
  AND token = 'Z6OgGGUgoE6EM5GlWH0ZcgC+TtFTQ1TEwU990qvwGBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}