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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b10db26ee1b8193832bc13e2f9b4d825a73be8eb8f368ccad44f1f22b3780d' 
  AND token = 'fk17AYpAei/FdI8mVn0CIIHP7WyOyW6KGhroA/jEoac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}