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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048ae00bc65c394265e28d0d4e1c82ffdcfb7a4d51e36e72081f9d8c56fec047' 
  AND token = 'DmjZjdKQFI7EnvIGBowLiyirAIjtpiPQ0j7r5n8JOFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}