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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c2647c38d1c6d8250fdda584c178898da0eb3957a3ef1fd8081b1f56526a8d' 
  AND token = '87BfhwnilIRPorjYfS4021PJ0jlHGNOlSGuj0CD2V5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}