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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8edc941bb61124e32544fa246d020d9bc5cffd3c5d1ab1e6a5afe4fb6c536814' 
  AND token = 'myaUDkX/2c6kHBL39RsgpYtJmz7Xxvu8cv+FrEphxns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}