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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ca01b14712ef4c7377de5636319cd51c5157620be51a6c3d6b0dee733c5250' 
  AND token = '4QJe4D9CZ+6Atxrsb3gzuMIAqfRBLox7GGOYNSn8naU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}