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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2b546ae415180d9dc119c68898b86954842fe598d44baabe1bf3553505c8be' 
  AND token = 'TC5AR3TUYV68jqyw8tN/qVtnNFx4cfUOF7tGMf0U+v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}