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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123963706e3ff63b04a29cecbe9074aa21138fcf3695031e74a936705a17f9ef' 
  AND token = 'GZ0F5INm9MWLclAHm5lu0x4JXPX3wvacRXL6j4pqVSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}