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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1430c9bbf908bf71d1ce60d4f78bc300c7a8f65a20d6838bb7bf009f8e72a4e4' 
  AND token = 'oEEbPwvDpDgNi1ne1BBxNtlDMh7a/JaK1iCJ48ojVgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}