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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf077b20c84d152c4dc51453c49b73942a68401544991cd7b76a2c297d6b17d' 
  AND token = 'tLqLA6m4qo5cuS4nmlVMsOS/HzA8JxGVdGuS/fwySPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}