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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e488974633edac01b2022d071878b1c1e1d948e57f27cd59dd34a34f4c45eb' 
  AND token = 'uMlj+yisxyhcG+aVmQeYRGEdnqsaXpcBb6acYFpnNio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}