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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9972e0ad07b66be278cf7ea3c6881eeb80364223e2cd177575c0a93248e3aca1' 
  AND token = 'tAmWQvS0cjSYn+TCoOzuMnUEuU3fFrwrINs1uw5N2XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}