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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb29e1154ba042ba7e32cc4fdb0fb72476855c77e033f8d28bbe8c9c8899ae09' 
  AND token = 'W721vQCLVk+lfPAWWQZb3GCCQjL4vRTGNWuUqpxVPBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}