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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404d52a4814b6a9178d7bd28c324c5ac43dc10e326092a9426b4aa9dbbe8a724' 
  AND token = '3EndVXKE4IW1cNE9gonTfsUWAYPIHuXoZf8HYtAb4os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}