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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6e01d78cb0569bced7c3ac13ed1d726ff0a10a8f72015d6dcb27ce5f2b7850' 
  AND token = 'd7tCYnX2BndseFND5muE5gDq8HfCpbAceR4EcNlveHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}