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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec00ec30f0e6d08e13cb6cf6298313118ee7e77718fe6fdced01c4f11ef5462f' 
  AND token = 'JSdekdch1XOxjnuAqarA0AZ3bH05imLj8v+TvWv+MN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}