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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2eeb8ae47361ea6791e6c2d6fd99e652442e6652ff17d9afd355e5e465e543c' 
  AND token = 'XDNZ7pvMXYHd3TTEyDyuxzqT3Fnwx/vFNk94dAmsy68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}