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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be84cb0af898b90e4d11612e5a42635190255f00da219bf0187aba7f54a9b587' 
  AND token = '8X2t7PQh6tfbrR2QEoa5AayzRZ66E8C71pOL5lMVWRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}