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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '319b26999ab9bdf12ac8ed2c303966d9bd56ad6063f4045dd1dd4eabaa27a0bc' 
  AND token = '1D08tanjdLI/uDCDlvt+0V1htB4vOQ4Vmc56tRI45Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}